The potential of infra-low frequency neurofeedback training in peak performance: The first double-blinded placebo-controlled longitudinal study in healthy adults.
This small trial found no clear advantage over sham for the measured performance, well-being or heart-rate-variability outcomes. It does not answer whether clinical populations might respond differently.
Schmidt C.
Journal of psychiatric research · Publication date: 2024-04-23
Added to site: 2026-09-09
DOI: 10.1016/j.jpsychires.2024.04.035
Publication date from the authoritative indexed record; this historical addition is not newly published news.
- Modalities
- Neurofeedback, ILF
- Clinical focus
- Cognition, Attention, Stress
- Population
- Healthy psychology students, ages 18–35
- Sample
- 42 participants
- Intervention / method
- Ten 30-minute ILF sessions over five weeks
- Comparator
- Sham ILF training under double-blind conditions
Clinician summary
After adjustment for baseline differences and multiple comparisons, no tested outcome significantly differed between groups. Assessments included two-month follow-up.
How to interpret the findings
Small sample could miss modest effects. Healthy-student results cannot settle efficacy for diagnosed conditions; favorable questionnaire correlations are not evidence of treatment benefit.
Equipment and disclosures
Equipment details were not verified from the reviewed abstract.
The indexed record lists Aalborg University support. Full competing-interest disclosures were not verified.
Related evidence
Compare findings from the same clinical area, including mixed results.
- Multimodal evidence associated with 20Hz rTMS in AD: neuroaxonal injury reduction, neural oscillatory rebalancing, and multilayer network integration · Positive with limitations
- Synergistic modulation of the dorsolateral prefrontal cortex and precuneus enhances cognitive recovery in mild cognitive impairment: A multimodal neuroimaging study · Positive with limitations
- Error Related Negativity and Error Positivity: Neural Indices of Double-Faults in Elite Athletes. · Positive with limitations
- Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans. · Positive with limitations
- The effect of heart rate variability biofeedback training on stress and anxiety: a meta-analysis. · Positive with limitations
- Attention, Executive Function, Behavior, and Electrocortical Function, Significantly Improved With 19-Channel Z-Score Neurofeedback in a Clinical Setting: A Pilot Study. · Positive with limitations
- Slow Cortical Potential Versus Live Z-score Neurofeedback in Children and Adolescents with ADHD: A Multi-arm Pragmatic Randomized Controlled Trial with Active and Passive Comparators. · Mixed
- Infra-low frequency neurofeedback impact on post-concussive symptoms of headache, insomnia and attention disorder: Results of a randomized control trial. · Positive with limitations
- Regulation in acute stress experience through functional near-infrared spectroscopy neurofeedback of the prefrontal cortex. · Positive with limitations
- Modulation of neuroendocrine and autonomic responses to competitive stress by slow cortical potentials training in golfers: An exploratory randomized controlled trial. · Mixed
- Clinical efficacy of non-pharmacological interventions on cognitive improvement in patients with mild to moderate Alzheimer's disease: A systematic review and Bayesian network meta-analysis. · Positive with limitations
- Personalized Brain Stimulation based on Brain Oscillations: A Systematic Review of MEG- and EEG-informed Transcranial Alternating Current Stimulation (tACS). · Positive with limitations
- Acute Psychophysiological Effects Of 4-7-8 And Nadi Shodhana Breathing: A Randomized Crossover Study. · Mixed
- Bilateral Angular Gyrus 810-nm Transcranial Near-Infrared Stimulation Reshapes Brain Network: Ameliorate Alzheimer's Disease Cognitive Deficits. · Positive with limitations
- Effects and safety of repetitive transcranial magnetic stimulation on cognitive outcomes in mild cognitive impairment: a systematic review and meta-analysis · Positive with limitations
- Multimodal Neurorehabilitation Including Auditory EEG Neurofeedback: A Proof of Concept Tested After Resection of a Giant Olfactory Groove Meningioma · Positive with limitations
- Temporal-Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial. · Positive with limitations
- The Effects of Alpha-Theta EEG Biofeedback Training on Anxiety and Stress: Novel Use of Hair Cortisol Concentration as a Biomarker · Positive with limitations
Summary prepared with AI assistance. Source verification does not imply an independent replication or a clinician's endorsement. Read our review method.