Validation of Low-Frequency Oscillatory Activity as an Indicator of Post-Stroke Injury and Recovery.

Repeated EEG measurements tracked patterns associated with motor recovery, supporting further biomarker research rather than proving treatment benefit.

Mark JI, Gangwani R, Snyder C, Cassidy JM.
Clinical EEG and neuroscience · Publication date: 2026-09-22
Added to site: 2026-09-23
DOI: 10.1177/15500594261488982

Electronic publication date verified in Europe PMC; first indexed 2026-09-23. This source date is separate from the site's addition date.

Modalities

EEG, QEEG

Clinical focus

Stroke, Motor recovery, Biomarkers

Population

Inpatient stroke rehabilitation participants

Sample

30 people after stroke and 17 unimpaired controls

Intervention / method

Resting EEG and motor assessments near admission and discharge, with structural imaging

Comparator

Unimpaired adults and repeated measurements

Clinician summary

Elevated interhemispheric motor delta coherence declined during rehabilitation. Coherence and power also correlated with structural injury.

How to interpret the findings

Observational associations cannot establish causality, treatment efficacy or individual prognosis. Diagnostic thresholds, external clinical utility and detailed safety reporting were not established.

Equipment and disclosures

EEG hardware and electrode count were not available in the checked abstract.

Funding and competing-interest details were not available in the checked indexed record.

Related evidence

Compare findings from the same clinical area, including mixed results.

• Acupuncture combined with repetitive transcranial magnetic stimulation vs repetitive transcranial magnetic stimulation alone for recovery of hemiparesis after ischemic stroke: A systematic review and meta-analysis. · Positive with limitations
• Pain Outcomes and Exercise Data from the EXERT-Stroke Pilot Clinical Trial on Post-Stroke Headaches. · Mixed
• Excitation/inhibition balance subtypes in autism and their genetic, neural, and clinical profiles. · Positive with limitations
• Motor Improvements Following Non-Invasive Brain Stimulation with kTMP: A Case Study of Cerebellar Stroke. · Positive with limitations
• Neuromodulation effects of HF-rTMS and rPMS on stroke patients: an fNIRS study. · Positive with limitations
• Clinical efficacy evaluation of combined central and peripheral repetitive transcranial magnetic stimulation for elbow flexor (biceps Brachii) spasticity and upper limb motor function after stroke · Positive with limitations