Explorative investigation on effects of multi-day neurofeedback with implanted electrodes in patients with Parkinson's disease.
Participants changed a recorded brain rhythm in some sessions, showing feasibility. This does not demonstrate symptom improvement.
Rohr-Fukuma M, Stieglitz LH, Bujan B, Imbach LL, Gassert R, Bichsel O.
Neuroscience · Publication date: 2026-06-24
Added to site: 2026-09-14
DOI: 10.1016/j.neuroscience.2026.06.016
First electronic publication June 24, 2026; September issue date is not new publication. Historical library addition.
- Modalities
- Neurofeedback
- Clinical focus
- Parkinson's disease
- Population
- People with Parkinson's disease and an implanted DBS system
- Sample
- Eight participants
- Intervention / method
- Three sessions on separate days using subthalamic signals for visual neurofeedback
- Comparator
- Upregulation and downregulation tasks; no randomized sham arm described in the abstract
Clinician summary
Beta power declined in sessions one and three, but cumulative regulation ability did not significantly improve. Medication and stimulation associations were exploratory.
How to interpret the findings
Small sample, invasive recordings and short observation. Findings cannot be generalized to scalp EEG neurofeedback.
Equipment and disclosures
Fully implanted deep-brain-stimulation sensing system; manufacturer not verified from abstract.
PubMed reproduces the authors’ declaration of no known competing financial interests or influential personal relationships. Funding was not verified.
Related evidence
Compare findings from the same clinical area, including mixed results.
- Anisotropic conductivity modeling for tDCS in Parkinson’s disease using multidimensional diffusion MRI · Positive with limitations
- Noninvasive brain stimulation for motor function and quality of life in Parkinson’s disease: a systematic review and network meta-analysis · Positive with limitations
- High-frequency rTMS over supplementary motor or primary motor cortex on reach-to-grasp in Parkinson's disease: A randomised controlled trial. · Positive with limitations
- Subthalamic DBS Engages Right-lateralized Frontal Control to Improve Gait Adaptation in Parkinson's Disease. · Positive with limitations
Summary prepared with AI assistance. Source verification does not imply an independent replication or a clinician's endorsement. Read our review method.