Resonance Frequency Breathing Intervention Modifies Cardiac Autonomic Response During a Metabolic Challenge

Published online October 13, 2026. After four weeks of resonance breathing with HRV feedback, healthy adults showed a smaller early drop in selected HRV measures during a glucose challenge. The study did not test symptoms, diabetes treatment or long-term health outcomes.

Peters LP, Heni M, Peter A, Hummel J, Kubiak T, Herhaus B, Petrowski K.
Applied Psychophysiology and Biofeedback · Publication date: 2026-10-13
Added to site: 2026-10-19
DOI: 10.1007/s10484-026-09813-6

First published online October 13, 2026. Added to Neurofeedback.com October 19, 2026.

Modalities

HRV biofeedback, Resonance-frequency breathing, Biofeedback

Clinical focus

Autonomic regulation, Metabolic challenge, Healthy adults

Population

Healthy young adults

Sample

28 participants, including 16 women; mean age 25.68 years

Intervention / method

Participants completed four weeks of resonance-frequency breathing with HRV biofeedback. RMSSD and SDNN responses during the first 30 minutes of a 75 g oral glucose tolerance test were compared before and after training.

Comparator

Within-participant pre-intervention versus post-intervention response during the standardized glucose challenge; no separate control group reported in the abstract

Clinician summary

Piecewise mixed-effects models found less pronounced early declines in log-transformed RMSSD and SDNN during the post-training oral glucose tolerance test. The result suggests changed short-term autonomic response dynamics rather than improved glucose control or clinical benefit.

How to interpret the findings

Small healthy-young-adult sample, single-group pre-post design, no separately reported control group, surrogate short-term physiology and no clinical outcome. Glucose values, durability, adverse-event detail and between-group effects were not available in the checked abstract.

Equipment and disclosures

The checked abstract does not identify the HRV acquisition or biofeedback-system manufacturer. No BrainMaster attribution.

Crossref lists support from Johannes Gutenberg University Mainz. M. Heni reported outside lecture fees and advisory-board roles with several pharmaceutical companies; the other authors reported no conflicts. No indexed correction, retraction or concern relation appeared in the retained PubMed or Crossref records; this is a bounded check. AI-assisted review.

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