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MixedRandomized active-comparator clinical study

Comparison of the Clinical Effectiveness of Two Photobiomodulation Systems for Facial Nerve Dysfunction Following Temporomandibular Joint Surgery.

Facial function improved over time in both PBM groups. Because every participant received active treatment and postoperative nerves may recover naturally, the study cannot show how much improvement was caused by PBM.

Yıldız M, Ayazoğlu M, Kamal A, Yurttutan ME, Altundoğan S, Cambazoğlu M.
Lasers in surgery and medicine · Publication date: 2026-09-23
Added to site: 2026-09-25
DOI: 10.1002/lsm.70213

Electronic publication date verified in Europe PMC; first indexed 2026-09-24. This source date is separate from the site's addition date.

Modalities
Photobiomodulation, Low-level laser therapy
Clinical focus
Facial nerve dysfunction, Jaw surgery, Postoperative recovery
Population
Patients who developed postoperative facial nerve dysfunction after jaw-joint surgery between May 2022 and April 2026
Sample
24 patients with facial nerve dysfunction after temporomandibular-joint surgery
Intervention / method
Fifteen PBM sessions beginning on postoperative day 1, daily for five days and every other day thereafter, with follow-up through day 60
Comparator
GRR Laser versus SiroLaser Advance Plus, with no sham or untreated recovery group

Clinician summary

Longitudinal mixed-effects models found significant time effects but no group or group-by-time effects. Day-5-to-day-60 change scores favored GRR on Sunnybrook and FaCE scales, while House-Brackmann grades did not differ between systems.

How to interpret the findings

Only 24 participants and no sham or usual-care comparator. Recovery over time cannot be separated from treatment effects. The abstract does not provide allocation concealment, blinding, wavelength and dose details, adverse-event reporting, or complete conflicts.

Equipment and disclosures

GRR Laser and SiroLaser Advance Plus systems were compared; the checked abstract did not report their wavelengths or dose parameters.

Supported by Ankara University grant TSG-2023-2856. Competing-interest details were not available in the checked indexed record.

Related evidence

Compare findings from the same clinical area, including mixed results.

Abstract checked · Checked 2026-09-25

Summary prepared with AI assistance. Source verification does not imply an independent replication or a clinician's endorsement. Read our review method.