A NeuroImage proof-of-concept reports a prediction-free method for timing transcranial magnetic stimulation to ongoing EEG rhythms. The system updated its phase measurement every millisecond and triggered pulses across eight target phases and ten frequencies from 4 to 40 Hz.
What the researchers found Mean stimulation phase was 5.6 degrees from target. Typical single-pulse error was 3.7 degrees, with trial-to-trial variability of 7.8 degrees. These measurements suggest that high-precision, phase-specific stimulation can be achieved without forecasting the signal ahead.
Why it matters Brain state can influence responses to stimulation. More accurate timing could help researchers test that relationship and may eventually inform individualized protocols.
What the evidence supports This is a technical feasibility result, not evidence of better clinical outcomes. The reviewed abstract does not report the participant count, and it does not compare symptom improvement, durability or safety across treatment strategies.
Published September 9, 2026. Funding and conflicts were not verified from the abstract. Prepared with AI assistance and checked against the authoritative indexed record on September 10, 2026.