Published September 25, 2026, in Brain Sciences, this single-case report followed a 53-year-old man after emergency resection of a giant olfactory groove meningioma. Severe bilateral visual impairment made standard visual feedback difficult.
A sensory-adapted program The patient completed 20 inpatient sessions across four weeks. Each session combined auditory SMR/theta EEG neurofeedback at Cz with individualized cognitive training and physiotherapy. The researchers also collected pre-post 19-channel resting EEG and analyzed single-channel recordings from the training sessions.
What changed Measurement-based improvements were reported in global cognition, executive functioning, immediate and delayed verbal recall, functional independence and mobility. The longitudinal EEG analysis retained 9,936 of 10,261 epochs and described lower theta activity with higher SMR and beta measures. The patient completed all 20 sessions, supporting practical feasibility of auditory feedback in this setting.
What the case cannot show This was one person with no control condition. Surgery, reduction in edema, spontaneous recovery, medication, sleep, cognitive training, physiotherapy and routine care may all have contributed. EEG analyses were descriptive, there was no delayed follow-up and the study cannot isolate a neurofeedback-specific effect.
Why it matters The useful advance is not proof of efficacy. It is a concrete example of adapting feedback to a patient's sensory needs inside coordinated rehabilitation. Controlled studies comparing rehabilitation with and without neurofeedback are needed.
Source and disclosure Full text checked. The work received partial support from the Italian Ministry of Health's Ricerca Corrente scheme; the authors declared no conflicts and disclosed ChatGPT use for language editing. Prepared with AI assistance and source-checked September 27, 2026.